by Taeryon Choi, Seongil Jo, Hyungjoon Kim and Hyotae Kim.

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This program stands for the people who study toxicology and who want to calculate the benchmark dose for some dose-response data.

For the estimation of a dose-response curve, BSAR(a Bayesian method for shape-restricted regression using a spectral analysis of Gaussian process priors) is implemented. Three different methods are used to calculate benchmark dose using estimated curve with BSAR, such as a method using cutoff value(Crump, 2002), benchmark response(Ritz, 2013) and benchmark response factor(U.S. EPA, 2014).

The program of graphical user interface is downloadable(BMD_BSAR_GUI_1.3.zip, BMD_BSAR_GUI_1.3.z01, BMD_BSAR_GUI_1.3.z02, BMD_BSAR_GUI_1.3.z03). To implement the program, after extracting the archives in the same folder,  the executable file(BMD_BSAR_GUI_v130.exe) which you can easily find from the folder named MainProgram must be executed.

We provide a simple manual for using BMD-BSAR. 

Last updated on July 10, 2015